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Benchling Article

How to avoid dauer-associated effects on longevity under reduced Insulin/IGF-1 signaling in the nematode Caenorhabditis elegans

Reduced Insulin/IGF-1 signaling (rIIS) increases lifespan in the nematode Caenorhabditis elegans, flies, and mice. This signaling pathway is the most studied longevity intervention in C. elegans. However, rIIS pathway also regulates a developmental arrest stage that can be activated improperly during adulthood. In the article, we discuss methods to avoid dauer-associated effects on longevity.

Twitter: ‏@benchling 
Studying how to prolong a worm’s life? @CollinEwald shares with Benchling two new ways to control for dauer:

A special thanks to the Benchling team.

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