@ ETH Zürich
Publications
Full texts
Also check our contributions on Github for details: https://github.com/Ewaldlab-LSD
Tail Tendon Break Time for the Assessment of Aging and Longitudinal Healthspan in Mice
Bio-Protocol
#Collagen #crosslinking is a major pathology during #aging, however, it is difficult to assess. @AnneHaefke shows how to use the "Tail Tendon Break Time for the Assessment of #Aging and Longitudinal #Healthspan in #Mice". @bioprotocolbyte #ewaldlab @eth
https://bio-protocol.org/e3833
Combining Auxin-Induced Degradation and RNAi Screening Identifies Novel Genes Involved in Lipid Bilayer Stress Sensing in Caenorhabditis elegans
G3: GENES, GENOMES, GENETICS
Double RNAi does not work so well, especially challenging for screening. Combining the power of #RNAi #screening with #auxin #degradation does the trick. We found 8 genes that had not previously been implicated in the #lipid #bilayer #stress #response.
The extracellular matrix phenome across species
Matrix Biology Plus
The in-silico characterization of the Caenorhabditis elegans matrisome and proposal of a novel collagen classification
Matrix Biology Plus. 2019 https://doi.org/10.1016/j.mbplus.2018.11.001
Alina C. Teuscher, Elisabeth Jongsma, Martin N.Davis, Cyril Statzer, Jan M.Gebauer, Alexandra Naba, Collin Y. Ewald
Paper is open access
Browse our C. elegans collagen database (CeColDB): http://CeColDB.permalink.cc/
Use our Matrisome Annotator on your datasets: http://ce-matrisome-annotator.permalink.cc/
Social Media Responses:
@DrGTWU: https://twitter.com/DrGTWU/status/1111509706386952193
"Thank you, @CollinEwald, for this foundational work, and to @ewbank_lab for sharing! My group will be increasing the citation index of this work! Dr. G added,"
@ishier_raote: https://twitter.com/ishier_raote/status/1111544341191901184
"A very useful resource indeed!"
@CSwormlab: https://twitter.com/NabaLabUIC/status/1111244387533709319
"Looking forward to using this resource! Congrats!"
@ewbank_lab: https://twitter.com/ewbank_lab/status/1111172814315372544
"http://www.sciencedirect.com/science/article/pii/S2590028518300012 …: Thorough classification of #C_elegans #matrisome by @CollinEwald et al; analysis of 181 #collagens. Will be very useful resource for those interested in ECM. A bonus: categorization of hits from our #RNAi screen for #immune genes http://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0256-3 …"
Overcoming Autofluorescence to Assess GFP Expression During Normal Physiology and Aging in Caenorhabditis elegans
Bio Protocol
https://bio-protocol.org/bio101/e2940
Will be in Europe PMC plus soon.
Until then, click on link below
Separating Autofluorescence from GFP and YFP with Microscope Filter Sets
WormAtlas
Assessing Collagen Deposition During Aging in Mammalian Tissue and in Caenorhabditis elegans
Methods Mol Biol. 2019;1944:169-188. doi: 10.1007/978-1-4939-9095-5_13.
Teuscher AC, Statzer C, Pantasis S, Bordoli MR, Ewald CY.
- PMID:30840243
Will be in Europe PMC plus soon. Until then, click on link below for Full-text
- https://uploads.strikinglycdn.com/files/17a30587-1bd4-4baa-9679-2899fae1bdd2/Teuscher2019_Protocol_AssessingCollagenDepositionDur.pdf?id=158111
Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging
Antioxidants (Basel). 2018 Sep 28;7(10). pii: E130. doi: 10.3390/antiox7100130. Review.
Untangling Longevity, Dauer, and Healthspan in Caenorhabditis elegans Insulin/IGF-1-Signalling
Gerontology
https://doi.org/10.1159/000480504
Will be open access in PubmedCentral in 2019.
Until then, click on link below
https://uploads.strikinglycdn.com/files/7cd52196-1465-45a5-b826-7d58960056d5/480504.pdf?id=84610
